Vol. 6, Issue 1, Part A (2024)

Introduction: Glaucoma is a chronic progressive optic neuropathy leading to irreversible blindness, emphasizing the need for early diagnosis and effective management. Anterior segment optical coherence tomography (AS-OCT) has emerged as a critical tool for diagnosing and monitoring glaucoma, offering high-resolution imaging of anterior segment structures and aiding in the evaluation of various glaucoma subtypes.
Method: This prospective observational study, conducted at the Department of Ophthalmology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, aimed to assess the relationship between intraocular pressure (IOP) and anterior chamber angle configurations using gonioscopy and AS-OCT. A total of 102 glaucoma patients aged 50 and older were included. Various ocular parameters were measured, including visual acuity, central corneal thickness (CCT), anterior chamber depth (ACD), and angle measurements via AS-OCT and gonioscopy.
Result: The study revealed a higher prevalence of angle-closure glaucoma (52%) and primary open-angle glaucoma (48%). Significant variations in iris configurations and angle structures were observed, with 64.7% of patients having open angles and 19.6% showing peripheral anterior synechiae. The study found a significant difference in ACA measurements between AS-OCT and gonioscopy (p<0.001).
Conclusion: AS-OCT offers valuable insights into the evaluation and monitoring of glaucoma, demonstrating a high degree of accuracy in assessing anterior chamber angles and iris configurations, complementing traditional diagnostic techniques.